This article first appeared in The Checkup, MIT Technology Review’s weekly biotech newsletter. To receive it in your inbox every Thursday, and read articles like this first, sign up here. Every journalist has favorite topics. Regular Checkup readers might already know some of mine, which include the quest to delay or reverse human aging, and new technologies for reproductive health and fertility. So when I saw trailers for The Substance, a film centered on one middle-aged woman’s attempt to reexperience youth, I had to watch it. I won’t spoil the movie for anyone…