Computational model helps with diabetes drug design

For diabetes patients who must give themselves frequent insulin injections, the risk of low blood sugar can be life-threatening. A potential solution is a type of engineered insulin that circulates in the body and springs into action only when needed. Researchers working on this type of “glucose-responsive insulin” (GRI) hope that it could be injected less often and help the body maintain normal blood sugar levels for longer periods of time. To help in the efforts to develop this kind of insulin, MIT engineers have created a computational model that…

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