Researchers have discovered a new stress signaling system that enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics. An enzyme, RlmN, was observed to directly sense chemical and environmental stresses, and rapidly signal for the production of other proteins that allow the bacteria cell to adapt and survive. This breakthrough discovery of RlmN as a stress sensor has revealed a new mechanism of antimicrobial resistance that can be targeted for drug development. The work was carried out by researchers from the Antimicrobial Resistance (AMR)…
