Using an innovative microscopy method, scientists at The Picower Institute for Learning and Memory at MIT observed how newborn neurons struggle to reach their proper places in advanced human brain tissue models of Rett syndrome, producing new insight into how developmental deficits observed in the brains of patients with the devastating disorder may emerge. Rett syndrome, which is characterized by symptoms including severe intellectual disability and impaired social behavior, is caused by mutations in the gene MECP2. To gain new insight into how the mutation affects the early stages of…
