It’s a classic visual illusion: Two gray dots appear on a background that consists of a gradient from light gray to black. Although the two dots are identical, they appear very different based on where they are placed against the background. Scientists who study the brain have been trying to figure out the mechanism behind this illusion, known as simultaneous brightness contrast, for more than 100 years. An MIT-led study now suggests that this phenomenon relies on brightness estimation that takes place before visual information reaches the brain’s visual cortex,…