In 2020, more than 278,000 people died from substance use disorder with over 91,000 of those from overdoses. Just three years later, deaths from overdoses alone rose by over 25,000. Despite its magnitude, the substance use disorder crisis still faces fundamental challenges: a prevailing societal stigma, lack of knowledge around its origin in the brain, and the slow pace of innovation in comparison to other diseases.Work at MIT is contributing to meaningful innovations in the field of substance use disorder, according to Hanna Adeyema MBA ’13, director of MIT Bootcamps at…