Deep machine-learning speeds assessment of fruit fly heart aging and disease, a model for human disease

Drosophila — commonly known as fruit flies — are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy. However, a choke point in evaluating fruit fly hearts is the need for human intervention to measure the heart at moments of its largest expansion or its greatest contraction, measurements that allow calculations of cardiac dynamics. Researchers at the University of Alabama at Birmingham now show a way to significantly cut the time needed for that analysis while utilizing more of the heart region, using deep learning and high-speed…

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