One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it. This step can account for up to half of the total cost of manufacturing a protein. In an effort to help reduce those costs, MIT engineers have devised a new way to perform this kind of purification. Their approach, which uses specialized nanoparticles to rapidly crystallize proteins, could help to make protein drugs more affordable and accessible, especially in developing countries….
